Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

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Detalles Bibliográficos
Autores principales: Hu, Chengcheng, Zhou, Mi, Wang, Wenzhao, Sun, Xianyun, Yarden, Oded, Li, Shaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776110/
https://www.ncbi.nlm.nih.gov/pubmed/29387050
http://dx.doi.org/10.3389/fmicb.2018.00009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776110/
https://www.ncbi.nlm.nih.gov/pubmed/29387050
http://dx.doi.org/10.3389/fmicb.2018.00009

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