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PK-PD Integration Modeling and Cutoff Value of Florfenicol against Streptococcus suis in Pigs

The aims of the present study were to establish optimal doses and provide an alternate CO(PD) for florfenicol against Streptococcus suis based on pharmacokinetic-pharmacodynamic integration modeling. The recommended dose (30 mg/kg b.w.) were administered in healthy pigs through intramuscular and int...

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Detalles Bibliográficos
Autores principales: Lei, Zhixin, Liu, Qianying, Yang, Shuaike, Yang, Bing, Khaliq, Haseeb, Li, Kun, Ahmed, Saeed, Sajid, Abdul, Zhang, Bingzhou, Chen, Pin, Qiu, Yinsheng, Cao, Jiyue, He, Qigai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776115/
https://www.ncbi.nlm.nih.gov/pubmed/29387013
http://dx.doi.org/10.3389/fphar.2018.00002