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CNS Neurons Deposit Laminin α5 to Stabilize Synapses

Synapses in the developing brain are structurally dynamic but become stable by early adulthood. We demonstrate here that an α5-subunit-containing laminin stabilizes synapses during this developmental transition. Hippocampal neurons deposit laminin α5 at synapses during adolescence as connections sta...

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Detalles Bibliográficos
Autores principales: Omar, Mitchell H., Campbell, Meghan Kerrisk, Xiao, Xiao, Zhong, Qiaonan, Brunken, William J., Miner, Jeffrey H., Greer, Charles A., Koleske, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776391/
https://www.ncbi.nlm.nih.gov/pubmed/29091766
http://dx.doi.org/10.1016/j.celrep.2017.10.028