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CNS Neurons Deposit Laminin α5 to Stabilize Synapses
Synapses in the developing brain are structurally dynamic but become stable by early adulthood. We demonstrate here that an α5-subunit-containing laminin stabilizes synapses during this developmental transition. Hippocampal neurons deposit laminin α5 at synapses during adolescence as connections sta...
Autores principales: | Omar, Mitchell H., Campbell, Meghan Kerrisk, Xiao, Xiao, Zhong, Qiaonan, Brunken, William J., Miner, Jeffrey H., Greer, Charles A., Koleske, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776391/ https://www.ncbi.nlm.nih.gov/pubmed/29091766 http://dx.doi.org/10.1016/j.celrep.2017.10.028 |
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