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Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling

OBJECTIVE(S): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced glycation end products (AGEs). MATERIALS AND METHODS:...

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Detalles Bibliográficos
Autores principales: Lu, Ming, Luo, Ying, Hu, Pengfei, Dou, Liping, Huang, Shuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776441/
https://www.ncbi.nlm.nih.gov/pubmed/29372041
http://dx.doi.org/10.22038/IJBMS.2017.20100.5276