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Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling
OBJECTIVE(S): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced glycation end products (AGEs). MATERIALS AND METHODS:...
Autores principales: | Lu, Ming, Luo, Ying, Hu, Pengfei, Dou, Liping, Huang, Shuwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776441/ https://www.ncbi.nlm.nih.gov/pubmed/29372041 http://dx.doi.org/10.22038/IJBMS.2017.20100.5276 |
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