Design, synthesis, and biological evaluation of 6-methoxy-2-arylquinolines as potential P-glycoprotein inhibitors

OBJECTIVE(S): In the present study, a new series of 6-methoxy-2-arylquinoline analogues was designed and synthesized as P-glycoprotein (P-gp) inhibitors using quinine and flavones as the lead compounds. MATERIALS AND METHODS: The cytotoxic activity of the synthesized compounds was evaluated against...

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Detalles Bibliográficos
Autores principales: Aboutorabzadeh, Sayyed Mohammad, Mosaffa, Fatemeh, Hadizadeh, Farzin, Ghodsi, Razieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776443/
https://www.ncbi.nlm.nih.gov/pubmed/29372031
http://dx.doi.org/10.22038/IJBMS.2017.21892.5616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776443/
https://www.ncbi.nlm.nih.gov/pubmed/29372031
http://dx.doi.org/10.22038/IJBMS.2017.21892.5616

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