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The effect of metabolic stress on genome stability of a synthetic biology chassis Escherichia coli K12 strain

BACKGROUND: Synthetic organism-based biotechnologies are increasingly being proposed for environmental applications, such as in situ sensing. Typically, the novel function of these organisms is delivered by compiling genetic fragments in the genome of a chassis organism. To behave predictably, these...

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Detalles Bibliográficos
Autores principales: Couto, Jillian M., McGarrity, Anne, Russell, Julie, Sloan, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776760/
https://www.ncbi.nlm.nih.gov/pubmed/29357936
http://dx.doi.org/10.1186/s12934-018-0858-2