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Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

Circulating influenza viruses evade neutralization in their human hosts by acquiring escape mutations at epitopes of prevalent antibodies. A goal for next-generation influenza vaccines is to reduce escape likelihood by selectively eliciting antibodies recognizing conserved surfaces on the viral hema...

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Detalles Bibliográficos
Autores principales: Raymond, Donald D., Bajic, Goran, Ferdman, Jack, Suphaphiphat, Pirada, Settembre, Ethan C., Moody, M. Anthony, Schmidt, Aaron G., Harrison, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776812/
https://www.ncbi.nlm.nih.gov/pubmed/29255041
http://dx.doi.org/10.1073/pnas.1715471115