Osteopontin deletion drives hematopoietic stem cell mobilization to the liver and increases hepatic iron contributing to alcoholic liver disease

The aim of this study was to investigate the role of osteopontin (OPN) in hematopoietic stem cell (HPSC) mobilization to the liver and its contribution to alcoholic liver disease (ALD). We analyzed young (14‐16 weeks) and old (>1.5 years) wild‐type (WT) littermates and global Opn knockout (Opn(−/...

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Detalles Bibliográficos
Autores principales: Magdaleno, Fernando, Ge, Xiaodong, Fey, Holger, Lu, Yongke, Gaskell, Harriet, Blajszczak, Chuck C., Aloman, Costica, Fiel, M. Isabel, Nieto, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776866/
https://www.ncbi.nlm.nih.gov/pubmed/29404515
http://dx.doi.org/10.1002/hep4.1116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776866/
https://www.ncbi.nlm.nih.gov/pubmed/29404515
http://dx.doi.org/10.1002/hep4.1116

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