Deficiency of cholesterol 7α‐hydroxylase in bile acid synthesis exacerbates alcohol‐induced liver injury in mice

Alcoholic fatty liver disease (AFLD) is a major risk factor for cirrhosis‐associated liver diseases. Studies demonstrate that alcohol increases serum bile acids in humans and rodents. AFLD has been linked to cholestasis, although the physiologic relevance of increased bile acids in AFLD and the unde...

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Detalles Bibliográficos
Autores principales: Donepudi, Ajay C., Ferrell, Jessica M., Boehme, Shannon, Choi, Hueng‐Sik, Chiang, John Y.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776875/
https://www.ncbi.nlm.nih.gov/pubmed/29404516
http://dx.doi.org/10.1002/hep4.1129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776875/
https://www.ncbi.nlm.nih.gov/pubmed/29404516
http://dx.doi.org/10.1002/hep4.1129

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