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Antimalarial Activity of C-10 Substituted Triazolyl Artemisinin

We synthesized C-10 substituted triazolyl artemisinins by the Huisgen cycloaddition reaction between dihydroartemisinins (2) and variously substituted 1, 2, 3-triazoles (8a-8h). The antimalarial activities of 32 novel artemisinin derivatives were screened against a chloroquine-resistant parasite. Am...

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Detalles Bibliográficos
Autores principales:	Park, Gab-Man, Park, Hyun, Oh, Sangtae, Lee, Seokjoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Parasitology and Tropical Medicine 2017
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776900/ https://www.ncbi.nlm.nih.gov/pubmed/29320822 http://dx.doi.org/10.3347/kjp.2017.55.6.661

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