Cytotoxic effect of Efavirenz in BxPC-3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation

The non-nucleoside reverse transcriptase inhibitor (NNRTI) Efavirenz is frequently used in human immunodeficiency virus treatment, but also efficient against cancer in mouse models. Its radiosensitizing effect makes it a promising drug for combination with radiotherapy. The efficacy of Efavirenz com...

Descripción completa

Detalles Bibliográficos
Autores principales: Hecht, Markus, Harrer, Thomas, Körber, Verena, Sarpong, Eric O., Moser, Fabian, Fiebig, Nora, Schwegler, Manuela, Stürzl, Michael, Fietkau, Rainer, Distel, Luitpold V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776903/
https://www.ncbi.nlm.nih.gov/pubmed/29434868
http://dx.doi.org/10.3892/ol.2017.7523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776903/
https://www.ncbi.nlm.nih.gov/pubmed/29434868
http://dx.doi.org/10.3892/ol.2017.7523

Ejemplares similares