Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas

Promoter methylation of P15, P16, RB transcriptional corepressor 1 (RB1) and O-6-methylguanine-DNA methyltransferase (MGMT) impacts the prognosis of numerous glioma subtypes. However, whether promoter methylation of these genes also has an impact on the clinical course of pilocytic astrocytoma remai...

Descripción completa

Detalles Bibliográficos
Autores principales: Sippl, Christoph, Urbschat, Steffi, Kim, Yoo Jin, Senger, Sebastian, Oertel, Joachim, Ketter, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776924/
https://www.ncbi.nlm.nih.gov/pubmed/29434855
http://dx.doi.org/10.3892/ol.2017.7490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776924/
https://www.ncbi.nlm.nih.gov/pubmed/29434855
http://dx.doi.org/10.3892/ol.2017.7490

Ejemplares similares