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Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas
Promoter methylation of P15, P16, RB transcriptional corepressor 1 (RB1) and O-6-methylguanine-DNA methyltransferase (MGMT) impacts the prognosis of numerous glioma subtypes. However, whether promoter methylation of these genes also has an impact on the clinical course of pilocytic astrocytoma remai...
Autores principales: | Sippl, Christoph, Urbschat, Steffi, Kim, Yoo Jin, Senger, Sebastian, Oertel, Joachim, Ketter, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776924/ https://www.ncbi.nlm.nih.gov/pubmed/29434855 http://dx.doi.org/10.3892/ol.2017.7490 |
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