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Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells

Mucin 1 (MUC1) is a high molecular weight transmembrane glycoprotein, that is overexpressed in >90% of breast cancers. It serves a crucial role in anti-apoptosis and tumor progression. MUC1 interacts with proteins in the extracellular matrix, at the cell membrane, in the cytoplasm and in the nucl...

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Detalles Bibliográficos
Autores principales: Gornowicz, Agnieszka, Bielawska, Anna, Szymanowski, Wojciech, Gabryel-Porowska, Halina, Czarnomysy, Robert, Bielawski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776928/
https://www.ncbi.nlm.nih.gov/pubmed/29434943
http://dx.doi.org/10.3892/ol.2017.7623