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Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells
Mucin 1 (MUC1) is a high molecular weight transmembrane glycoprotein, that is overexpressed in >90% of breast cancers. It serves a crucial role in anti-apoptosis and tumor progression. MUC1 interacts with proteins in the extracellular matrix, at the cell membrane, in the cytoplasm and in the nucl...
Autores principales: | Gornowicz, Agnieszka, Bielawska, Anna, Szymanowski, Wojciech, Gabryel-Porowska, Halina, Czarnomysy, Robert, Bielawski, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776928/ https://www.ncbi.nlm.nih.gov/pubmed/29434943 http://dx.doi.org/10.3892/ol.2017.7623 |
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