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Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions

High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The objective of the present study was to analyze HPV L1 gene methylation and to...

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Detalles Bibliográficos
Autores principales: Torres-Rojas, Francisco Israel, Alarcón-Romero, Luz del Carmen, Leyva-Vázquez, Marco Antonio, Ortiz-Ortiz, Julio, Mendoza-Catalán, Miguel Ángel, Hernández-Sotelo, Daniel, Del Moral-Hernández, Oscar, Rodríguez-Ruiz, Hugo Alberto, Leyva-Illades, Dinorah, Flores-Alfaro, Eugenia, Illades-Aguiar, Berenice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776931/
https://www.ncbi.nlm.nih.gov/pubmed/29434935
http://dx.doi.org/10.3892/ol.2017.7596