Cargando…

A novel synthetic ursolic acid derivative inhibits growth and induces apoptosis in breast cancer cell lines

The present study investigated the anticancer functions of ursolic acid (UA) and its novel derivatives, with a nitrogen-containing heterocyclic scaffold and the privileged fragment at the C-28 position on apoptosis induction, cell proliferation and cell cycle in human BC lines. UA was chemically mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wei, Zhang, Hongxiu, Nie, Mingxiu, Wang, Wei, Liu, Zongtao, Chen, Ceshi, Chen, Haijun, Liu, Rong, Baloch, Zulqarnain, Ma, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776946/
https://www.ncbi.nlm.nih.gov/pubmed/29434940
http://dx.doi.org/10.3892/ol.2017.7578