Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

The contribution of host genetic and nongenetic factors to immunological differences in humans remains largely undefined. Here, we generated bacterial-, fungal-, and viral-induced immune transcriptional profiles in an age- and sex-balanced cohort of 1,000 healthy individuals and searched for the det...

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Detalles Bibliográficos
Autores principales: Piasecka, Barbara, Duffy, Darragh, Urrutia, Alejandra, Quach, Hélène, Patin, Etienne, Posseme, Céline, Bergstedt, Jacob, Charbit, Bruno, Rouilly, Vincent, MacPherson, Cameron R., Hasan, Milena, Albaud, Benoit, Gentien, David, Fellay, Jacques, Albert, Matthew L., Quintana-Murci, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776984/
https://www.ncbi.nlm.nih.gov/pubmed/29282317
http://dx.doi.org/10.1073/pnas.1714765115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776984/
https://www.ncbi.nlm.nih.gov/pubmed/29282317
http://dx.doi.org/10.1073/pnas.1714765115

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