Engineering posttranslational proofreading to discriminate nonstandard amino acids

Incorporation of nonstandard amino acids (nsAAs) leads to chemical diversification of proteins, which is an important tool for the investigation and engineering of biological processes. However, the aminoacyl-tRNA synthetases crucial for this process are polyspecific in regard to nsAAs and standard...

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Detalles Bibliográficos
Autores principales: Kunjapur, Aditya M., Stork, Devon A., Kuru, Erkin, Vargas-Rodriguez, Oscar, Landon, Matthieu, Söll, Dieter, Church, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776986/
https://www.ncbi.nlm.nih.gov/pubmed/29301968
http://dx.doi.org/10.1073/pnas.1715137115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776986/
https://www.ncbi.nlm.nih.gov/pubmed/29301968
http://dx.doi.org/10.1073/pnas.1715137115

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