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RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases
Directed migration is essential for cell motility in many processes, including development and cancer cell invasion. RSKs (p90 ribosomal S6 kinases) have emerged as central regulators of cell migration; however, the mechanisms mediating RSK-dependent motility remain incompletely understood. We have...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777029/ https://www.ncbi.nlm.nih.gov/pubmed/29279389 http://dx.doi.org/10.1073/pnas.1708584115 |