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Inhibition of focal adhesion kinase overcomes resistance of mantle cell lymphoma to ibrutinib in the bone marrow microenvironment

Mantle cell lymphoma and other lymphoma subtypes often spread to the bone marrow, and stromal interactions mediated by focal adhesion kinase frequently enhance survival and drug resistance of the lymphoma cells. To study the role of focal adhesion kinase in mantle cell lymphoma, immunohistochemistry...

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Detalles Bibliográficos
Autores principales: Rudelius, Martina, Rosenfeldt, Mathias Tillmann, Leich, Ellen, Rauert-Wunderlich, Hilka, Solimando, Antonio Giovanni, Beilhack, Andreas, Ott, German, Rosenwald, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777199/
https://www.ncbi.nlm.nih.gov/pubmed/29079592
http://dx.doi.org/10.3324/haematol.2017.177162