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Rps26 directs mRNA-specific translation by recognition of Kozak sequence elements

We describe a novel approach to separate two ribosome populations from the same cells and use this method, and RNA-seq, to identify the mRNAs bound to S. cerevisiae ribosomes with and without Rps26, a protein linked to the pathogenesis of Diamond Blackfan Anemia (DBA). These analyses reveal that Rps...

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Detalles Bibliográficos
Autores principales: Ferretti, Max B., Ghalei, Homa, Ward, Ethan A., Potts, Elizabeth L., Karbstein, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777333/
https://www.ncbi.nlm.nih.gov/pubmed/28759050
http://dx.doi.org/10.1038/nsmb.3442