Population pharmacodynamic modelling of midazolam induced sedation in terminally ill adult patients

AIMS: Midazolam is the drug of choice for palliative sedation and is titrated to achieve the desired level of sedation. A previous pharmacokinetic (PK) study showed that variability between patients could be partly explained by renal function and inflammatory status. The goal of this study was to co...

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Detalles Bibliográficos
Autores principales: Franken, Linda G., de Winter, Brenda C. M., Masman, Anniek D., van Dijk, Monique, Baar, Frans P. M., Tibboel, Dick, Koch, Birgit C. P., van Gelder, Teun, Mathot, Ron A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777431/
https://www.ncbi.nlm.nih.gov/pubmed/28960387
http://dx.doi.org/10.1111/bcp.13442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777431/
https://www.ncbi.nlm.nih.gov/pubmed/28960387
http://dx.doi.org/10.1111/bcp.13442

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