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Identification of the histone lysine demethylase KDM4A/JMJD2A as a novel epigenetic target in M1 macrophage polarization induced by oxidized LDL

Oxidized low density lipoprotein (oxLDL) induces macrophage activation, an event essential for atherosclerosis. Emerging evidence supports that epigenetic regulation plays important roles in macrophage activation and function. However, it remains unclear which epigenetic modulator is responsible for...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Wang, Siqing, Yao, Gang, Yu, Dehai, Chen, Kexin, Tong, Qian, Ye, Long, Wu, Chuan, Sun, Yue, Li, Haixia, Hermann, Dirk M., Doeppner, Thorsten R., Jin, Fengyan, Dai, Yun, Wu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777704/
https://www.ncbi.nlm.nih.gov/pubmed/29383092
http://dx.doi.org/10.18632/oncotarget.17748