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Hypoxia-inducible factor-1α promotes cell survival during ammonia stress response in ovarian cancer stem-like cells

Ammonia is a toxic by-product of metabolism that causes cellular stresses. Although a number of proteins are involved in adaptive stress response, specific factors that counteract ammonia-induced cellular stress and regulate cell metabolism to survive against its toxicity have yet to be identified....

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Detalles Bibliográficos
Autores principales: Kitajima, Shojiro, Lee, Kian Leong, Hikasa, Hiroki, Sun, Wendi, Huang, Ruby Yun-Ju, Yang, Henry, Matsunaga, Shinji, Yamaguchi, Takehiro, Araki, Marito, Kato, Hiroyuki, Poellinger, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777708/
https://www.ncbi.nlm.nih.gov/pubmed/29383096
http://dx.doi.org/10.18632/oncotarget.23010