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Targeting the SUMO pathway as a novel treatment for anaplastic thyroid cancer

Cancer stem cells (CSCs) are expanded in anaplastic thyroid cancer (ATC) and standard treatment approaches have failed to improve survival, suggesting a need to specifically target the CSC population. Recent studies in breast and colorectal cancer demonstrated that inhibition of the SUMO pathway rep...

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Detalles Bibliográficos
Autores principales: De Andrade, James P., Lorenzen, Allison W., Wu, Vincent T., Bogachek, Maria V., Park, Jung M., Gu, Vivian W., Sevenich, Claire M., Cassady, Victoria C., Beck, Anna C., Kulak, Mikhail V., Robinson, Robert A., Lal, Geeta, Weigel, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777733/
https://www.ncbi.nlm.nih.gov/pubmed/29383121
http://dx.doi.org/10.18632/oncotarget.21954