Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo

Breast cancer is the most prevalent malignancy in women and there is an urgent need for new therapeutic drugs targeting aggressive and metastatic subtypes, such as hormone-refractory triple-negative breast cancer (TNBC). Control of protein synthesis is vital to cell growth and tumour progression and...

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Detalles Bibliográficos
Autores principales: Sesé, Marta, Fuentes, Pedro, Esteve-Codina, Anna, Béjar, Eva, McGrail, Kimberley, Thomas, George, Aasen, Trond, Ramón y Cajal, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777738/
https://www.ncbi.nlm.nih.gov/pubmed/29383126
http://dx.doi.org/10.18632/oncotarget.23145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777738/
https://www.ncbi.nlm.nih.gov/pubmed/29383126
http://dx.doi.org/10.18632/oncotarget.23145

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