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Norcantharidin alone or in combination with crizotinib induces autophagic cell death in hepatocellular carcinoma by repressing c-Met-mTOR signaling

There is an urgent need for effective molecular therapies for hepatocellular carcinoma (HCC), the third-leading cause of cancer-related deaths worldwide. Norcantharidin (NCTD), a demethylated derivative of cantharidin, reportedly exhibits anticancer activity against various types of tumors, includin...

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Detalles Bibliográficos
Autores principales: Sun, Chao-Yue, Zhu, Ying, Li, Xiao-Feng, Tang, Li-Peng, Su, Zu-Qing, Wang, Xie-Qi, Li, Cai-Yun, Yang, Hong-Mei, Zheng, Guang-Juan, Feng, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777744/
https://www.ncbi.nlm.nih.gov/pubmed/29383132
http://dx.doi.org/10.18632/oncotarget.22935