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Cigarette smoke enhances initiation and progression of lung cancer by mutating Notch1/2 and dysregulating downstream signaling molecules

Lung cancer is the primary cause of cancer related deaths in the western world and smoking significantly increases the risk of developing lung cancer. Smoking enhances lung cancer initiation and progression. The effects of cigarette smoke on lung cancer are mediated by the presence of highly mutagen...

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Detalles Bibliográficos
Autores principales: Li, Wei, Zhou, Jihong, Chen, Yuqing, Zhang, Gengyan, Jiang, Peng, Hong, Lei, Shen, Yuangbing, Wang, Xiaojing, Gong, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777759/
https://www.ncbi.nlm.nih.gov/pubmed/29383147
http://dx.doi.org/10.18632/oncotarget.22924