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HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients

Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT seems to derive from multipotent embryonic renal stem cells that have failed to differentiate properly. Since mechanisms underlying WT tumorigenesis remain largely unknown, the aim o...

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Detalles Bibliográficos
Autores principales: Hontecillas-Prieto, Lourdes, García-Domínguez, Daniel J., García-Mejías, Rosa, Ramírez-Villar, Gema L., Sáez, Carmen, de Álava, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777772/
https://www.ncbi.nlm.nih.gov/pubmed/29383160
http://dx.doi.org/10.18632/oncotarget.23256