Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion

Gemcitabine, an anti-cancer chemotherapy drug, has additionally shown the antiviral activity against a broad range of viruses and we also have previously reported its synergistic antiviral activity with ribavirin against enteroviruses. As a cytidine analog, gemcitabine has been reported to have an i...

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Detalles Bibliográficos
Autores principales: Lee, Kyungjin, Kim, Dong-Eun, Jang, Kyoung-Soon, Kim, Seong-Jun, Cho, Sungchan, Kim, Chonsaeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777774/
https://www.ncbi.nlm.nih.gov/pubmed/29383162
http://dx.doi.org/10.18632/oncotarget.23258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777774/
https://www.ncbi.nlm.nih.gov/pubmed/29383162
http://dx.doi.org/10.18632/oncotarget.23258

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