P53-derived hybrid peptides induce apoptosis of synovial fibroblasts in the rheumatoid joint

Loss of p53-mediated suppression by its dominant-negative counterpart is commonly observed in human cancers, and activating p73 is a therapeutic strategy in p53-mutated oncological patients. In synovial fibroblasts (SFs) from rheumatoid arthritis (RA), mutant p53 can lead to the transformation-like...

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Detalles Bibliográficos
Autores principales: Chen, Shih-Yao, Shiau, Ai-Li, Wu, Chao-Liang, Wang, Chrong-Reen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777781/
https://www.ncbi.nlm.nih.gov/pubmed/29383169
http://dx.doi.org/10.18632/oncotarget.23268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777781/
https://www.ncbi.nlm.nih.gov/pubmed/29383169
http://dx.doi.org/10.18632/oncotarget.23268

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