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P53-derived hybrid peptides induce apoptosis of synovial fibroblasts in the rheumatoid joint
Loss of p53-mediated suppression by its dominant-negative counterpart is commonly observed in human cancers, and activating p73 is a therapeutic strategy in p53-mutated oncological patients. In synovial fibroblasts (SFs) from rheumatoid arthritis (RA), mutant p53 can lead to the transformation-like...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777781/ https://www.ncbi.nlm.nih.gov/pubmed/29383169 http://dx.doi.org/10.18632/oncotarget.23268 |