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Dimeric and tetrameric forms of muscle fructose-1,6-bisphosphatase play different roles in the cell

Muscle fructose 1,6-bisphosphatase (FBP2), besides being a regulatory enzyme of glyconeogenesis also protects mitochondria against calcium stress and plays a key role in regulation of the cell cycle, promoting cardiomyocytes survival. However, in cancer cells, FBP2 acts as an anti-oncogenic/anti-pro...

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Detalles Bibliográficos
Autores principales: Wiśniewski, Janusz, Piróg, Michał, Hołubowicz, Rafał, Dobryszycki, Piotr, McCubrey, James A., Rakus, Dariusz, Gizak, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777782/
https://www.ncbi.nlm.nih.gov/pubmed/29383170
http://dx.doi.org/10.18632/oncotarget.23271