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Dimeric and tetrameric forms of muscle fructose-1,6-bisphosphatase play different roles in the cell
Muscle fructose 1,6-bisphosphatase (FBP2), besides being a regulatory enzyme of glyconeogenesis also protects mitochondria against calcium stress and plays a key role in regulation of the cell cycle, promoting cardiomyocytes survival. However, in cancer cells, FBP2 acts as an anti-oncogenic/anti-pro...
Autores principales: | Wiśniewski, Janusz, Piróg, Michał, Hołubowicz, Rafał, Dobryszycki, Piotr, McCubrey, James A., Rakus, Dariusz, Gizak, Agnieszka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777782/ https://www.ncbi.nlm.nih.gov/pubmed/29383170 http://dx.doi.org/10.18632/oncotarget.23271 |
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