Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis

BACKGROUND: Organic cation transporters (OCT) are responsible for the uptake of a broad spectrum of endogenous and exogenous substrates. Downregulation of OCT is frequently observed in human hepatocellular carcinoma (HCC) and is associated with a poor outcome. The aim of our current study was to elu...

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Detalles Bibliográficos
Autores principales: Vollmar, Johanna, Lautem, Anja, Closs, Ellen, Schuppan, Detlef, Kim, Yong Ook, Grimm, Daniel, Marquardt, Jens U., Fuchs, Peter, Straub, Beate K., Schad, Arno, Gründemann, Dirk, Schattenberg, Jörn M., Gehrke, Nadine, Wörns, Marcus A., Baumgart, Jan, Galle, Peter R., Zimmermann, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777802/
https://www.ncbi.nlm.nih.gov/pubmed/29383190
http://dx.doi.org/10.18632/oncotarget.23372