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Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis
BACKGROUND: Organic cation transporters (OCT) are responsible for the uptake of a broad spectrum of endogenous and exogenous substrates. Downregulation of OCT is frequently observed in human hepatocellular carcinoma (HCC) and is associated with a poor outcome. The aim of our current study was to elu...
Autores principales: | Vollmar, Johanna, Lautem, Anja, Closs, Ellen, Schuppan, Detlef, Kim, Yong Ook, Grimm, Daniel, Marquardt, Jens U., Fuchs, Peter, Straub, Beate K., Schad, Arno, Gründemann, Dirk, Schattenberg, Jörn M., Gehrke, Nadine, Wörns, Marcus A., Baumgart, Jan, Galle, Peter R., Zimmermann, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777802/ https://www.ncbi.nlm.nih.gov/pubmed/29383190 http://dx.doi.org/10.18632/oncotarget.23372 |
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