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Antibody-drug conjugates: recent advances in conjugation and linker chemistries
The antibody-drug conjugate (ADC), a humanized or human monoclonal antibody conjugated with highly cytotoxic small molecules (payloads) through chemical linkers, is a novel therapeutic format and has great potential to make a paradigm shift in cancer chemotherapy. This new antibody-based molecular p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Higher Education Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777969/ https://www.ncbi.nlm.nih.gov/pubmed/27743348 http://dx.doi.org/10.1007/s13238-016-0323-0 |