CD4(+) T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8(+) T Cell Function in the Pancreas

Autoreactive CD8(+) and CD4(+) T cells have been assigned independent key roles in the destruction of insulin-producing beta cells resulting in type 1 diabetes. Although CD4 help for the generation of efficient CD8(+) T cell responses in lymphoid tissue has been extensively described, whether these...

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Detalles Bibliográficos
Autores principales: Espinosa-Carrasco, Gabriel, Le Saout, Cécile, Fontanaud, Pierre, Stratmann, Thomas, Mollard, Patrice, Schaeffer, Marie, Hernandez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778106/
https://www.ncbi.nlm.nih.gov/pubmed/29403481
http://dx.doi.org/10.3389/fimmu.2017.02001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778106/
https://www.ncbi.nlm.nih.gov/pubmed/29403481
http://dx.doi.org/10.3389/fimmu.2017.02001

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