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The Aspergillus fumigatus Sialidase (Kdnase) Contributes to Cell Wall Integrity and Virulence in Amphotericin B-Treated Mice

Aspergillus fumigatus is a filamentous fungus that can cause a life-threatening invasive pulmonary aspergillosis (IPA) in immunocompromised individuals. We previously characterized an exo-sialidase from A. fumigatus that prefers the sialic acid substrate, 2-keto-3-deoxy-D-glycero-D-galacto-nononic a...

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Detalles Bibliográficos
Autores principales: Nesbitt, Jason R., Steves, Elizabeth Y., Schonhofer, Cole R., Cait, Alissa, Manku, Sukhbir S., Yeung, Juliana H. F., Bennet, Andrew J., McNagny, Kelly M., Choy, Jonathan C., Hughes, Michael R., Moore, Margo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778107/
https://www.ncbi.nlm.nih.gov/pubmed/29403452
http://dx.doi.org/10.3389/fmicb.2017.02706