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Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse
Full T cell activation requires coordination of signals from multiple receptor–ligand pairs that interact in parallel at a specialized cell–cell contact site termed the immunological synapse (IS). Signaling at the IS is intimately associated with actin dynamics; T cell receptor (TCR) engagement indu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778112/ https://www.ncbi.nlm.nih.gov/pubmed/29403502 http://dx.doi.org/10.3389/fimmu.2018.00025 |