Long-acting injectable atovaquone nanomedicines for malaria prophylaxis

Chemoprophylaxis is currently the best available prevention from malaria, but its efficacy is compromised by non-adherence to medication. Here we develop a long-acting injectable formulation of atovaquone solid drug nanoparticles that confers long-lived prophylaxis against Plasmodium berghei ANKA ma...

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Detalles Bibliográficos
Autores principales: Bakshi, Rahul P., Tatham, Lee M., Savage, Alison C., Tripathi, Abhai K., Mlambo, Godfree, Ippolito, Matthew M., Nenortas, Elizabeth, Rannard, Steve P., Owen, Andrew, Shapiro, Theresa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778127/
https://www.ncbi.nlm.nih.gov/pubmed/29358624
http://dx.doi.org/10.1038/s41467-017-02603-z