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Cell culture-based production of defective interfering particles for influenza antiviral therapy

Defective interfering particles (DIPs) lack an essential portion of the virus genome, but retain signals for replication and packaging, and therefore, interfere with standard virus (STV) replication. Due to this property, DIPs can be potential antivirals. The influenza A virus DIP DI244, generated d...

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Detalles Bibliográficos
Autores principales: Wasik, Milena A., Eichwald, Luca, Genzel, Yvonne, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778153/
https://www.ncbi.nlm.nih.gov/pubmed/29204901
http://dx.doi.org/10.1007/s00253-017-8660-3