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Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations
[Image: see text] Pan-Assay Interference Compounds (PAINS) are very familiar to medicinal chemists who have spent time fruitlessly trying to optimize these nonprogressible compounds. Electronic filters formulated to recognize PAINS can process hundreds and thousands of compounds in seconds and are i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778390/ https://www.ncbi.nlm.nih.gov/pubmed/29202222 http://dx.doi.org/10.1021/acschembio.7b00903 |