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DNA knots occur in intracellular chromatin

In vivo DNA molecules are narrowly folded within chromatin fibers and self-interacting chromatin domains. Therefore, intra-molecular DNA entanglements (knots) might occur via DNA strand passage activity of topoisomerase II. Here, we assessed the presence of such DNA knots in a variety of yeast circu...

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Detalles Bibliográficos
Autores principales: Valdés, Antonio, Segura, Joana, Dyson, Sílvia, Martínez-García, Belén, Roca, Joaquim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778459/
https://www.ncbi.nlm.nih.gov/pubmed/29149297
http://dx.doi.org/10.1093/nar/gkx1137