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Trypanosomatid mitochondrial RNA editing: dramatically complex transcript repertoires revealed with a dedicated mapping tool

RNA editing by targeted insertion and deletion of uridine is crucial to generate translatable mRNAs from the cryptogenes of the mitochondrial genome of kinetoplastids. This type of editing consists of a stepwise cascade of reactions generally proceeding from 3′ to 5′ on a transcript, resulting in a...

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Detalles Bibliográficos
Autores principales: Gerasimov, Evgeny S, Gasparyan, Anna A, Kaurov, Iosif, Tichý, Boris, Logacheva, Maria D, Kolesnikov, Alexander A, Lukeš, Julius, Yurchenko, Vyacheslav, Zimmer, Sara L, Flegontov, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778460/
https://www.ncbi.nlm.nih.gov/pubmed/29220521
http://dx.doi.org/10.1093/nar/gkx1202