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Fission yeast Ccq1 is a modulator of telomerase activity

Shelterin, the telomeric protein complex, plays a crucial role in telomere homeostasis. In fission yeast, telomerase is recruited to chromosome ends by the shelterin component Tpz1 and its binding partner Ccq1, where telomerase binds to the 3′ overhang to add telomeric repeats. Recruitment is initia...

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Detalles Bibliográficos
Autores principales: Armstrong, Christine A, Moiseeva, Vera, Collopy, Laura C, Pearson, Siân R, Ullah, Tomalika R, Xi, Shidong T, Martin, Jennifer, Subramaniam, Shaan, Marelli, Sara, Amelina, Hanna, Tomita, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778466/
https://www.ncbi.nlm.nih.gov/pubmed/29216371
http://dx.doi.org/10.1093/nar/gkx1223