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Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA

The conserved PAF1 complex (Cdc73, Paf1, Ctr9, Leo1 and Rtf1, in yeast), binds RNA pol II, and affects levels of many RNAs. Although PAF1 is a complex, there is evidence that different components perform different functions. In yeast, Cdc73, Paf1 and Ctr9 maintain normal telomerase RNA (TLC1) levels...

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Detalles Bibliográficos
Autores principales: Rodrigues, Joana, Lydall, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778495/
https://www.ncbi.nlm.nih.gov/pubmed/29145644
http://dx.doi.org/10.1093/nar/gkx1131